About Epithelial membrane protein 3
Epithelial membrane protein 3 (EMP3) is a protein
from Homo sapiens identified by UniProt accession
P54852, 163 residues long.
MolForge cross-references it against 0 known binders and
119 disease associations.
Target properties
| Protein name | Epithelial membrane protein 3 |
|---|
| UniProt accession | P54852 |
|---|
| Gene | EMP3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 163 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (119)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- glioblastoma multiforme · score 0.11
- breast carcinoma · score 0.09
- neoplasm · score 0.09
- Blackfan-Diamond anemia · score 0.08
- platelet count · score 0.08
- hepatocellular carcinoma · score 0.08
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.08
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54852-F1 | alphafold | PREDICTED | 90.92 | — |
Amino-acid sequence (163 residues)
MSLLLLVVSA LHILILILLF VATLDKSWWT LPGKESLNLW YDCTWNNDTK TWACSNVSEN GWLKAVQVLM VLSLILCCLS FILFMFQLYT MRRGGLFYAT GLCQLCTSVA VFTGALIYAI HAEEILEKHP RGGSFGYCFA LAWVAFPLAL VSGIIYIHLR KRE
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