About UDP-glucuronosyltransferase 2B15
UDP-glucuronosyltransferase 2B15 (UGT2B15) is a protein
from Homo sapiens identified by UniProt accession
P54855, 530 residues long.
MolForge cross-references it against 0 known binders and
81 disease associations.
Target properties
| Protein name | UDP-glucuronosyltransferase 2B15 |
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| UniProt accession | P54855 |
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| Gene | UGT2B15 |
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| Organism | Homo sapiens |
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| Length | 530 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (81)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.49
- serum gamma-glutamyl transferase measurement · score 0.48
- alkaline phosphatase measurement · score 0.47
- mean corpuscular volume · score 0.47
- testosterone measurement · score 0.47
- apolipoprotein A 1 measurement · score 0.43
- high density lipoprotein cholesterol measurement · score 0.43
- total cholesterol measurement · score 0.41
- bilirubin measurement · score 0.41
- mean corpuscular hemoglobin concentration · score 0.41
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54855-F1 | alphafold | PREDICTED | 93.36 | — |
Amino-acid sequence (530 residues)
MSLKWTSVFL LIQLSCYFSS GSCGKVLVWP TEYSHWINMK TILEELVQRG HEVTVLTSSA STLVNASKSS AIKLEVYPTS LTKNYLEDSL LKILDRWIYG VSKNTFWSYF SQLQELCWEY YDYSNKLCKD AVLNKKLMMK LQESKFDVIL ADALNPCGEL LAELFNIPFL YSLRFSVGYT FEKNGGGFLF PPSYVPVVMS ELSDQMIFME RIKNMIHMLY FDFWFQIYDL KKWDQFYSEV LGRPTTLFET MGKAEMWLIR TYWDFEFPRP FLPNVDFVGG LHCKPAKPLP KEMEEFVQSS GENGIVVFSL GSMISNMSEE SANMIASALA QIPQKVLWRF DGKKPNTLGS NTRLYKWLPQ NDLLGHPKTK AFITHGGTNG IYEAIYHGIP MVGIPLFADQ HDNIAHMKAK GAALSVDIRT MSSRDLLNAL KSVINDPVYK ENVMKLSRIH HDQPMKPLDR AVFWIEFVMR HKGAKHLRVA AHNLTWIQYH SLDVIAFLLA CVATVIFIIT KFCLFCFRKL AKKGKKKKRD
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