About Microfibrillar-associated protein 2
Microfibrillar-associated protein 2 (MFAP2) is a protein
from Homo sapiens identified by UniProt accession
P55001, 183 residues long.
MolForge cross-references it against 0 known binders and
205 disease associations.
Target properties
| Protein name | Microfibrillar-associated protein 2 |
|---|
| UniProt accession | P55001 |
|---|
| Gene | MFAP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 183 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (205)
Diseases linked to this target (Open Targets).
- body height · score 0.42
- vital capacity · score 0.41
- BMI-adjusted waist circumference · score 0.39
- neurodegenerative disease · score 0.38
- FEV/FVC ratio · score 0.36
- forced expiratory volume · score 0.36
- blood protein measurement · score 0.36
- body fat distribution · score 0.35
- smoking behavior · score 0.33
- appendicular lean mass · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55001-F1 | alphafold | PREDICTED | 69.34 | — |
Amino-acid sequence (183 residues)
MRAAYLFLLF LPAGLLAQGQ YDLDPLPPFP DHVQYTHYSD QIDNPDYYDY QEVTPRPSEE QFQFQSQQQV QQEVIPAPTP EPGNAELEPT EPGPLDCREE QYPCTRLYSI HRPCKQCLNE VCFYSLRRVY VINKEICVRT VCAHEELLRA DLCRDKFSKC GVMASSGLCQ SVAASCARSC GSC
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