About GTP-binding protein RAD
GTP-binding protein RAD (RRAD) is a protein
from Homo sapiens identified by UniProt accession
P55042, 308 residues long.
MolForge cross-references it against 0 known binders and
220 disease associations.
Target properties
| Protein name | GTP-binding protein RAD |
|---|
| UniProt accession | P55042 |
|---|
| Gene | RRAD |
|---|
| Organism | Homo sapiens |
|---|
| Length | 308 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (220)
Diseases linked to this target (Open Targets).
- heart rate · score 0.33
- neoplasm · score 0.08
- Arrhythmogenic right ventricular dysplasia · score 0.07
- Brugada syndrome · score 0.07
- oral squamous cell carcinoma · score 0.07
- hypertrophic cardiomyopathy · score 0.07
- Romano-Ward syndrome · score 0.07
- hepatocellular carcinoma · score 0.06
- Familial short QT syndrome · score 0.06
- dilated cardiomyopathy 1I · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55042-F1 | alphafold | PREDICTED | 73.40 | — |
Amino-acid sequence (308 residues)
MTLNGGGSGA GGSRGGGQER ERRRGSTPWG PAPPLHRRSM PVDERDLQAA LTPGALTAAA AGTGTQGPRL DWPEDSEDSL SSGGSDSDES VYKVLLLGAP GVGKSALARI FGGVEDGPEA EAAGHTYDRS IVVDGEEASL MVYDIWEQDG GRWLPGHCMA MGDAYVIVYS VTDKGSFEKA SELRVQLRRA RQTDDVPIIL VGNKSDLVRS REVSVDEGRA CAVVFDCKFI ETSAALHHNV QALFEGVVRQ IRLRRDSKEA NARRQAGTRR RESLGKKAKR FLGRIVARNS RKMAFRAKSK SCHDLSVL
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