About Apolipoprotein C-IV
Apolipoprotein C-IV (APOC4) is a protein
from Homo sapiens identified by UniProt accession
P55056, 127 residues long.
MolForge cross-references it against 0 known binders and
107 disease associations.
Target properties
| Protein name | Apolipoprotein C-IV |
|---|
| UniProt accession | P55056 |
|---|
| Gene | APOC4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 127 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (107)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.36
- low density lipoprotein cholesterol measurement · score 0.28
- high density lipoprotein cholesterol measurement · score 0.27
- apolipoprotein A 1 measurement · score 0.25
- total cholesterol measurement · score 0.25
- triglyceride measurement · score 0.24
- Red cell distribution width · score 0.24
- lung adenocarcinoma · score 0.23
- cutaneous melanoma · score 0.23
- granulocyte colony-stimulating factor measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55056-F1 | alphafold | PREDICTED | 76.31 | — |
Amino-acid sequence (127 residues)
MSLLRNRLQA LPALCLCVLV LACIGACQPE AQEGTLSPPP KLKMSRWSLV RGRMKELLET VVNRTRDGWQ WFWSPSTFRG FMQTYYDDHL RDLGPLTKAW FLESKDSLLK KTHSLCPRLV CGDKDQG
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