Microfibril-associated glycoprotein 3 (MFAP3)

About Microfibril-associated glycoprotein 3

Microfibril-associated glycoprotein 3 (MFAP3) is a protein from Homo sapiens identified by UniProt accession P55082, 362 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Microfibril-associated glycoprotein 3
UniProt accession	P55082
Gene	MFAP3
Organism	Homo sapiens
Length	362 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

body mass index · score 0.39
Red cell distribution width · score 0.33
sex hormone-binding globulin measurement · score 0.32
apolipoprotein A 1 measurement · score 0.30
lean body mass · score 0.27
body weight · score 0.27
body fat percentage · score 0.27
mathematical ability · score 0.26
self reported educational attainment · score 0.25
fat body mass · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55082-F1	alphafold	PREDICTED	61.43	—

Amino-acid sequence (362 residues)

MKLHCCLFTL VASIIVPAAF VLEDVDFDQM VSLEANRSSY NASFPSSFEL SASSHSDDDV IIAKEGTSVS IECLLTASHY EDVHWHNSKG QQLDGRSRGG KWLVSDNFLN ITNVAFDDRG LYTCFVTSPI RASYSVTLRV IFTSGDMSVY YMIVCLIAFT ITLILNVTRL CMMSSHLRKT EKAINEFFRT EGAEKLQKAF EIAKRIPIIT SAKTLELAKV TQFKTMEFAR YIEELARSVP LPPLILNCRA FVEEMFEAVR VDDPDDLGER IKERPALNAQ GGIYVINPEM GRSNSPGGDS DDGSLNEQGQ EIAVQVSVHL QSETKSIDTE SQGSSHFSPP DDIGSAESNC NYKDGAYENC QL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards