Inhibin beta C chain (INHBC)

About Inhibin beta C chain

Inhibin beta C chain (INHBC) is a protein from Homo sapiens identified by UniProt accession P55103, 352 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.

Target properties

Protein name	Inhibin beta C chain
UniProt accession	P55103
Gene	INHBC
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (84)

Diseases linked to this target (Open Targets).

high density lipoprotein cholesterol measurement · score 0.24
urate measurement · score 0.23
monocyte count · score 0.23
sex hormone-binding globulin measurement · score 0.22
triglyceride measurement · score 0.22
alkaline phosphatase measurement · score 0.21
hemoglobin measurement · score 0.21
apolipoprotein B measurement · score 0.21
low density lipoprotein cholesterol measurement · score 0.20
apolipoprotein A 1 measurement · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55103-F1	alphafold	PREDICTED	74.16	—

Amino-acid sequence (352 residues)

MTSSLLLAFL LLAPTTVATP RAGGQCPACG GPTLELESQR ELLLDLAKRS ILDKLHLTQR PTLNRPVSRA ALRTALQHLH GVPQGALLED NREQECEIIS FAETGLSTIN QTRLDFHFSS DRTAGDREVQ QASLMFFVQL PSNTTWTLKV RVLVLGPHNT NLTLATQYLL EVDASGWHQL PLGPEAQAAC SQGHLTLELV LEGQVAQSSV ILGGAAHRPF VAARVRVGGK HQIHRRGIDC QGGSRMCCRQ EFFVDFREIG WHDWIIQPEG YAMNFCIGQC PLHIAGMPGI AASFHTAVLN LLKANTAAGT TGGGSCCVPT ARRPLSLLYY DRDSNIVKTD IPDMVVEACG CS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards