Nucleosome assembly protein 1-like 1 (NAP1L1)

About Nucleosome assembly protein 1-like 1

Nucleosome assembly protein 1-like 1 (NAP1L1) is a protein from Homo sapiens identified by UniProt accession P55209, 391 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.

Target properties

Protein name	Nucleosome assembly protein 1-like 1
UniProt accession	P55209
Gene	NAP1L1
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (75)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin · score 0.30
red blood cell density measurement · score 0.28
cystatin C measurement · score 0.22
glomerular filtration rate · score 0.14
blood urea nitrogen measurement · score 0.14
creatinine measurement · score 0.13
intrathoracic organ injury · score 0.13
amyloid-beta measurement · score 0.12
atrial fibrillation · score 0.12
central nervous system cancer · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55209-F1	alphafold	PREDICTED	79.91	—

Amino-acid sequence (391 residues)

MADIDNKEQS ELDQDLDDVE EVEEEETGEE TKLKARQLTV QMMQNPQILA ALQERLDGLV ETPTGYIESL PRVVKRRVNA LKNLQVKCAQ IEAKFYEEVH DLERKYAVLY QPLFDKRFEI INAIYEPTEE ECEWKPDEED EISEELKEKA KIEDEKKDEE KEDPKGIPEF WLTVFKNVDL LSDMVQEHDE PILKHLKDIK VKFSDAGQPM SFVLEFHFEP NEYFTNEVLT KTYRMRSEPD DSDPFSFDGP EIMGCTGCQI DWKKGKNVTL KTIKKKQKHK GRGTVRTVTK TVSNDSFFNF FAPPEVPESG DLDDDAEAIL AADFEIGHFL RERIIPRSVL YFTGEAIEDD DDDYDEEGEE ADEEGEEEGD EENDPDYDPK KDQNPAECKQ Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards