About Caspase-7
Caspase-7 (CASP7) is a protein
from Homo sapiens identified by UniProt accession
P55210, 303 residues long.
MolForge cross-references it against 0 known binders and
217 disease associations.
Target properties
| Protein name | Caspase-7 |
|---|
| UniProt accession | P55210 |
|---|
| Gene | CASP7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 303 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (217)
Diseases linked to this target (Open Targets).
- cataract · score 0.45
- Vitiligo · score 0.36
- neurodegenerative disease · score 0.29
- Age-related cataract · score 0.29
- lens disease · score 0.28
- breast adenocarcinoma · score 0.26
- ovarian cancer · score 0.25
- esophageal cancer · score 0.23
- head and neck squamous cell carcinoma · score 0.23
- gastric adenocarcinoma · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55210-F1 | alphafold | PREDICTED | 81.71 | — |
Amino-acid sequence (303 residues)
MADDQGCIEE QGVEDSANED SVDAKPDRSS FVPSLFSKKK KNVTMRSIKT TRDRVPTYQY NMNFEKLGKC IIINNKNFDK VTGMGVRNGT DKDAEALFKC FRSLGFDVIV YNDCSCAKMQ DLLKKASEED HTNAACFACI LLSHGEENVI YGKDGVTPIK DLTAHFRGDR CKTLLEKPKL FFIQACRGTE LDDGIQADSG PINDTDANPR YKIPVEADFL FAYSTVPGYY SWRSPGRGSW FVQALCSILE EHGKDLEIMQ ILTRVNDRVA RHFESQSDDP HFHEKKQIPC VVSMLTKELY FSQ
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