About Adenosine kinase
Adenosine kinase (ADK) is a protein
from Homo sapiens identified by UniProt accession
P55263, 362 residues long.
MolForge cross-references it against 0 known binders and
233 disease associations.
Target properties
| Protein name | Adenosine kinase |
|---|
| UniProt accession | P55263 |
|---|
| Gene | ADK |
|---|
| Organism | Homo sapiens |
|---|
| Length | 362 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (3)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (233)
Diseases linked to this target (Open Targets).
- adenosine kinase deficiency · score 0.75
- body mass index · score 0.38
- platelet count · score 0.38
- neurodegenerative disease · score 0.32
- lean body mass · score 0.31
- tooth eruption · score 0.30
- FEV/FVC ratio · score 0.30
- creatinine measurement · score 0.30
- systolic blood pressure · score 0.28
- pulse pressure measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55263-F1 | alphafold | PREDICTED | 93.31 | — |
Amino-acid sequence (362 residues)
MAAAEEEPKP KKLKVEAPQA LRENILFGMG NPLLDISAVV DKDFLDKYSL KPNDQILAED KHKELFDELV KKFKVEYHAG GSTQNSIKVA QWMIQQPHKA ATFFGCIGID KFGEILKRKA AEAHVDAHYY EQNEQPTGTC AACITGDNRS LIANLAAANC YKKEKHLDLE KNWMLVEKAR VCYIAGFFLT VSPESVLKVA HHASENNRIF TLNLSAPFIS QFYKESLMKV MPYVDILFGN ETEAATFARE QGFETKDIKE IAKKTQALPK MNSKRQRIVI FTQGRDDTIM ATESEVTAFA VLDQDQKEII DTNGAGDAFV GGFLSQLVSD KPLTECIRAG HYAASIIIRR TGCTFPEKPD FH
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