About Cadherin-8
Cadherin-8 (CDH8) is a protein
from Homo sapiens identified by UniProt accession
P55286, 799 residues long.
MolForge cross-references it against 0 known binders and
71 disease associations.
Target properties
| Protein name | Cadherin-8 |
|---|
| UniProt accession | P55286 |
|---|
| Gene | CDH8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 799 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55286-F1 | alphafold | PREDICTED | 77.31 | — |
Amino-acid sequence (799 residues)
MPERLAEMLL DLWTPLIILW ITLPPCIYMA PMNQSQVLMS GSPLELNSLG EEQRILNRSK RGWVWNQMFV LEEFSGPEPI LVGRLHTDLD PGSKKIKYIL SGDGAGTIFQ INDVTGDIHA IKRLDREEKA EYTLTAQAVD WETSKPLEPP SEFIIKVQDI NDNAPEFLNG PYHATVPEMS ILGTSVTNVT ATDADDPVYG NSAKLVYSIL EGQPYFSIEP ETAIIKTALP NMDREAKEEY LVVIQAKDMG GHSGGLSGTT TLTVTLTDVN DNPPKFAQSL YHFSVPEDVV LGTAIGRVKA NDQDIGENAQ SSYDIIDGDG TALFEITSDA QAQDGIIRLR KPLDFETKKS YTLKVEAANV HIDPRFSGRG PFKDTATVKI VVEDADEPPV FSSPTYLLEV HENAALNSVI GQVTARDPDI TSSPIRFSID RHTDLERQFN INADDGKITL ATPLDRELSV WHNITIIATE IRNHSQISRV PVAIKVLDVN DNAPEFASEY EAFLCENGKP GQVIQTVSAM DKDDPKNGHY FLYSLLPEMV NNPNFTIKKN EDNSLSILAK HNGFNRQKQE VYLLPIIISD SGNPPLSSTS TLTIRVCGCS NDGVVQSCNV EAYVLPIGLS MGALIAILAC IILLLVIVVL FVTLRRHKNE PLIIKDDEDV RENIIRYDDE GGGEEDTEAF DIATLQNPDG INGFLPRKDI KPDLQFMPRQ GLAPVPNGVD VDEFINVRLH EADNDPTAPP YDSIQIYGYE GRGSVAGSLS SLESTTSDSD QNFDYLSDWG PRFKRLGELY SVGESDKET
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