Cadherin-13 (CDH13)

Homo sapiens — UniProt P55290

Gene: CDH13Homo sapiensSwissProt reviewed

About Cadherin-13

Cadherin-13 (CDH13) is a protein from Homo sapiens identified by UniProt accession P55290, 713 residues long. MolForge cross-references it against 0 known binders and 342 disease associations.

Target properties

Protein nameCadherin-13
UniProt accessionP55290
GeneCDH13
OrganismHomo sapiens
Length713 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (342)

Diseases linked to this target (Open Targets).

  • electrocardiography · score 0.52
  • adiponectin measurement · score 0.48
  • coronary artery disease · score 0.46
  • pulse pressure measurement · score 0.46
  • body mass index · score 0.46
  • diastolic blood pressure · score 0.43
  • body fat percentage · score 0.43
  • mathematical ability · score 0.42
  • BMI-adjusted adiponectin measurement · score 0.41
  • urate measurement · score 0.40

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P55290-F1alphafoldPREDICTED85.07—

Amino-acid sequence (713 residues)

MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI LNLTFSDCKG NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART PHAEDMAELV IVGGKDIQGS LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV DQEPKGIFRI NENTGSVSVT RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND NRPIFREGPY IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT IMIDDKNDHS PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY TIINGNPGQS FEIHTNPQTN EGMLSVVKPL DYEISAFHTL LIKVENEDPL VPDVSYGPSS TATVHITVLD VNEGPVFYPD PMMVTRQEDL SVGSVLLTVN ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD RESPFVDNSV YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL NKANYNLPIM VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP SVLLLSLFSL ACL

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Quick facts

UniProtP55290
GeneCDH13
OrganismHomo sapiens
Length713
Binders0
Diseases342
View on UniProt