About Tumor protein D52
Tumor protein D52 (TPD52) is a protein
from Homo sapiens identified by UniProt accession
P55327, 224 residues long.
MolForge cross-references it against 0 known binders and
113 disease associations.
Target properties
| Protein name | Tumor protein D52 |
|---|
| UniProt accession | P55327 |
|---|
| Gene | TPD52 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (113)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.44
- sex hormone-binding globulin measurement · score 0.41
- rheumatoid arthritis · score 0.39
- asthma · score 0.35
- testosterone measurement · score 0.34
- drug use measurement · score 0.33
- eosinophil percentage of leukocytes · score 0.32
- atopic eczema · score 0.32
- allergic rhinitis · score 0.31
- drug-induced liver injury · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55327-F1 | alphafold | PREDICTED | 68.08 | — |
Amino-acid sequence (224 residues)
MDCREMDLYE DYQSPFDFDA GVNKSYLYLS PSGNSSPPGS PTLQKFGLLR TDPVPEEGED VAATISATET LSEEEQEELR RELAKVEEEI QTLSQVLAAK EKHLAEIKRK LGINSLQELK QNIAKGWQDV TATSAYKKTS ETLSQAGQKA SAAFSSVGSV ITKKLEDVKN SPTFKSFEEK VENLKSKVGG TKPAGGDFGE VLNSAANASA TTTEPLPEKT QESL
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