Paired box protein Pax-9 (PAX9)

About Paired box protein Pax-9

Paired box protein Pax-9 (PAX9) is a protein from Homo sapiens identified by UniProt accession P55771, 341 residues long. MolForge cross-references it against 0 known binders and 501 disease associations.

Target properties

Protein name	Paired box protein Pax-9
UniProt accession	P55771
Gene	PAX9
Organism	Homo sapiens
Length	341 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (501)

Diseases linked to this target (Open Targets).

tooth agenesis · score 0.74
body height · score 0.48
breast carcinoma · score 0.47
osteoarthritis, knee · score 0.41
genetic disorder · score 0.41
neurodegenerative disease · score 0.39
prostate carcinoma · score 0.37
BMI-adjusted waist circumference · score 0.33
sitting height measurement · score 0.33
medical procedure · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55771-F1	alphafold	PREDICTED	63.44	—

Amino-acid sequence (341 residues)

MEPAFGEVNQ LGGVFVNGRP LPNAIRLRIV ELAQLGIRPC DISRQLRVSH GCVSKILARY NETGSILPGA IGGSKPRVTT PTVVKHIRTY KQRDPGIFAW EIRDRLLADG VCDKYNVPSV SSISRILRNK IGNLAQQGHY DSYKQHQPTP QPALPYNHIY SYPSPITAAA AKVPTPPGVP AIPGSVAMPR TWPSSHSVTD ILGIRSITDQ VSDSSPYHSP KVEEWSSLGR NNFPAAAPHA VNGLEKGALE QEAKYGQAPN GLPAVGSFVS ASSMAPYPTP AQVSPYMTYS AAPSGYVAGH GWQHAGGTSL SPHNCDIPAS LAFKGMQAAR EGSHSVTASA L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards