C-C motif chemokine 18 (CCL18)

About C-C motif chemokine 18

C-C motif chemokine 18 (CCL18) is a protein from Homo sapiens identified by UniProt accession P55774, 89 residues long. MolForge cross-references it against 0 known binders and 356 disease associations.

Target properties

Protein name	C-C motif chemokine 18
UniProt accession	P55774
Gene	CCL18
Organism	Homo sapiens
Length	89 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (356)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.25
protein measurement · score 0.22
C-C motif chemokine 18 measurement · score 0.22
C-C motif chemokine 3 measurement · score 0.20
C-C motif chemokine 3-like 1 measurement · score 0.15
CCL3 measurement · score 0.12
oral squamous cell carcinoma · score 0.11
neoplasm · score 0.11
chronic obstructive pulmonary disease · score 0.11
Rheumatoid arthritis · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55774-F1	alphafold	PREDICTED	86.49	—

Amino-acid sequence (89 residues)

MKGLAAALLV LVCTMALCSC AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards