Glycoprotein Xg (XG)

About Glycoprotein Xg

Glycoprotein Xg (XG) is a protein from Homo sapiens identified by UniProt accession P55808, 180 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Glycoprotein Xg
UniProt accession	P55808
Gene	XG
Organism	Homo sapiens
Length	180 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

primary ovarian insufficiency · score 0.12
central nervous system cancer · score 0.03
microphthalmia with limb anomalies · score 0.01
neoplasm · score 0.01
breast cancer · score 0.01
Ewing sarcoma · score 0.01
rosacea · score 0.01
ependymoma · score 0.01
atopic eczema · score 0.01
Adams-Oliver syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55808-F1	alphafold	PREDICTED	58.44	—

Amino-acid sequence (180 residues)

MESWWGLPCL AFLCFLMHAR GQRDFDLADA LDDPEPTKKP NSDIYPKPKP PYYPQPENPD SGGNIYPRPK PRPQPQPGNS GNSGGYFNDV DRDDGRYPPR PRPRPPAGGG GGGYSSYGNS DNTHGGDHHS TYGNPEGNMV AKIVSPIVSV VVVTLLGAAA SYFKLNNRRN CFRTHEPENV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards