Putative mitochondrial transporter UCP3 (UCP3)

About Putative mitochondrial transporter UCP3

Putative mitochondrial transporter UCP3 (UCP3) is a protein from Homo sapiens identified by UniProt accession P55916, 312 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.

Target properties

Protein name	Putative mitochondrial transporter UCP3
UniProt accession	P55916
Gene	UCP3
Organism	Homo sapiens
Length	312 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (122)

Diseases linked to this target (Open Targets).

morbid obesity · score 0.33
obesity · score 0.23
inherited obesity · score 0.23
MODY · score 0.08
type 2 diabetes mellitus · score 0.08
neoplasm · score 0.07
myocardial infarction · score 0.06
type 1 diabetes mellitus · score 0.06
diabetes mellitus, transient neonatal, 2 · score 0.05
FRAXF syndrome · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P55916-F1	alphafold	PREDICTED	62.68	—

Amino-acid sequence (312 residues)

MVGLKPSDVP PTMAVKFLGA GTAACFADLV TFPLDTAKVR LQIQGENQAV QTARLVQYRG VLGTILTMVR TEGPCSPYNG LVAGLQRQMS FASIRIGLYD SVKQVYTPKG ADNSSLTTRI LAGCTTGAMA VTCAQPTDVV KVRFQASIHL GPSRSDRKYS GTMDAYRTIA REEGVRGLWK GTLPNIMRNA IVNCAEVVTY DILKEKLLDY HLLTDNFPCH FVSAFGAGFC ATVVASPVDV VKTRYMNSPP GQYFSPLDCM IKMVAQEGPT AFYKGFTPSF LRLGSWNVVM FVTYEQLKRA LMKVQMLRES PF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards