About BH3-interacting domain death agonist
BH3-interacting domain death agonist (BID) is a protein
from Homo sapiens identified by UniProt accession
P55957, 195 residues long.
MolForge cross-references it against 0 known binders and
266 disease associations.
Target properties
| Protein name | BH3-interacting domain death agonist |
|---|
| UniProt accession | P55957 |
|---|
| Gene | BID |
|---|
| Organism | Homo sapiens |
|---|
| Length | 195 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (266)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- platelet count · score 0.37
- platelet crit · score 0.35
- body height · score 0.28
- breast adenocarcinoma · score 0.27
- hemoglobin measurement · score 0.27
- head and neck squamous cell carcinoma · score 0.27
- esophageal cancer · score 0.27
- lung adenocarcinoma · score 0.26
- body mass index · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P55957-F1 | alphafold | PREDICTED | 62.97 | — |
Amino-acid sequence (195 residues)
MDCEVNNGSS LRDECITNLL VFGFLQSCSD NSFRRELDAL GHELPVLAPQ WEGYDELQTD GNRSSHSRLG RIEADSESQE DIIRNIARHL AQVGDSMDRS IPPGLVNGLA LQLRNTSRSE EDRNRDLATA LEQLLQAYPR DMEKEKTMLV LALLLAKKVA SHTPSLLRDV FHTTVNFINQ NLRTYVRSLA RNGMD
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