ATP synthase F(0) complex subunit f, mitochondrial…

About ATP synthase F(0) complex subunit f, mitochondrial

ATP synthase F(0) complex subunit f, mitochondrial (ATP5MF) is a protein from Homo sapiens identified by UniProt accession P56134, 94 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit f, mitochondrial
UniProt accession	P56134
Gene	ATP5MF
Organism	Homo sapiens
Length	94 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.15
mean platelet volume · score 0.11
sex hormone-binding globulin measurement · score 0.09
platelet count · score 0.08
hemoglobin A1 measurement · score 0.08
blood metabolite measurement · score 0.08
body fat percentage · score 0.07
HbA1c measurement · score 0.07
X12063 measurement · score 0.07
allergic rhinitis · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P56134-F1	alphafold	PREDICTED	75.29	—

Amino-acid sequence (94 residues)

MASVGECPAP VPVKDKKLLE VKLGELPSWI LMRDFSPSGI FGAFQRGYYR YYNKYINVKK GSISGITMVL ACYVLFSYSF SYKHLKHERL RKYH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit f, mitochondrial (ATP5MF)