About Homeobox protein DLX-6
Homeobox protein DLX-6 (DLX6) is a protein
from Homo sapiens identified by UniProt accession
P56179, 175 residues long.
MolForge cross-references it against 0 known binders and
190 disease associations.
Target properties
| Protein name | Homeobox protein DLX-6 |
|---|
| UniProt accession | P56179 |
|---|
| Gene | DLX6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 175 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (190)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.45
- body height · score 0.44
- smoking status measurement · score 0.40
- Split hand-split foot malformation · score 0.37
- bone quantitative ultrasound measurement · score 0.36
- smoking initiation · score 0.35
- appendicular lean mass · score 0.35
- body fat percentage · score 0.30
- chronotype measurement · score 0.29
- smoking behavior · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56179-F1 | alphafold | PREDICTED | 68.66 | — |
Amino-acid sequence (175 residues)
MSHSQHSPYL QSYHNSSAAA QTRGDDTDQQ KTTVIENGEI RFNGKGKKIR KPRTIYSSLQ LQALNHRFQQ TQYLALPERA ELAASLGLTQ TQVKIWFQNK RSKFKKLLKQ GSNPHESDPL QGSAALSPRS PALPPVWDVS ASAKGVSMPP NSYMPGYSHW YSSPHQDTMQ RPQMM
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