About Cathepsin W
Cathepsin W (CTSW) is a protein
from Homo sapiens identified by UniProt accession
P56202, 376 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Cathepsin W |
|---|
| UniProt accession | P56202 |
|---|
| Gene | CTSW |
|---|
| Organism | Homo sapiens |
|---|
| Length | 376 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- body height · score 0.16
- self reported educational attainment · score 0.15
- Crohn's disease · score 0.15
- glioblastoma multiforme · score 0.14
- psoriasis · score 0.14
- ulcerative colitis · score 0.14
- sclerosing cholangitis · score 0.14
- ankylosing spondylitis · score 0.14
- monocyte count · score 0.13
- inflammatory bowel disease · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56202-F1 | alphafold | PREDICTED | 83.54 | — |
Amino-acid sequence (376 residues)
MALTAHPSCL LALLVAGLAQ GIRGPLRAQD LGPQPLELKE AFKLFQIQFN RSYLSPEEHA HRLDIFAHNL AQAQRLQEED LGTAEFGVTP FSDLTEEEFG QLYGYRRAAG GVPSMGREIR SEEPEESVPF SCDWRKVASA ISPIKDQKNC NCCWAMAAAG NIETLWRISF WDFVDVSVQE LLDCGRCGDG CHGGFVWDAF ITVLNNSGLA SEKDYPFQGK VRAHRCHPKK YQKVAWIQDF IMLQNNEHRI AQYLATYGPI TVTINMKPLQ LYRKGVIKAT PTTCDPQLVD HSVLLVGFGS VKSEEGIWAE TVSSQSQPQP PHPTPYWILK NSWGAQWGEK GYFRLHRGSN TCGITKFPLT ARVQKPDMKP RVSCPP
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