cAMP-regulated phosphoprotein 19 (ARPP19)

About cAMP-regulated phosphoprotein 19

cAMP-regulated phosphoprotein 19 (ARPP19) is a protein from Homo sapiens identified by UniProt accession P56211, 112 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	cAMP-regulated phosphoprotein 19
UniProt accession	P56211
Gene	ARPP19
Organism	Homo sapiens
Length	112 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.08
hepatocellular carcinoma · score 0.06
laryngeal carcinoma · score 0.03
neoplasm · score 0.02
calcium measurement · score 0.02
mean platelet volume · score 0.02
oral squamous cell carcinoma · score 0.02
glioblastoma multiforme · score 0.02
cancer · score 0.01
Down syndrome · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P56211-F1	alphafold	PREDICTED	68.48	—

Amino-acid sequence (112 residues)

MSAEVPEAAS AEEQKEMEDK VTSPEKAEEA KLKARYPHLG QKPGGSDFLR KRLQKGQKYF DSGDYNMAKA KMKNKQLPTA APDKTEVTGD HIPTPQDLPQ RKPSLVASKL AG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards