ATP synthase F(0) complex subunit j, mitochondrial…

About ATP synthase F(0) complex subunit j, mitochondrial

ATP synthase F(0) complex subunit j, mitochondrial (ATP5MJ) is a protein from Homo sapiens identified by UniProt accession P56378, 58 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit j, mitochondrial
UniProt accession	P56378
Gene	ATP5MJ
Organism	Homo sapiens
Length	58 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

adolescent idiopathic scoliosis · score 0.11
amino acid measurement · score 0.11
asparagine measurement · score 0.11
alcohol use disorder measurement · score 0.08
blood metabolite measurement · score 0.08
diet measurement · score 0.05
unipolar depression · score 0.04
schizophrenia · score 0.03
refractive error · score 0.03
retinal layer thickness measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P56378-F1	alphafold	PREDICTED	86.48	—

Amino-acid sequence (58 residues)

MLQSIIKNIW IPMKPYYTKV YQEIWIGMGL MGFIVYKIRA ADKRSKALKA SAPAPGHH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit j, mitochondrial (ATP5MJ)