ATP synthase F(0) complex subunit e, mitochondrial…

About ATP synthase F(0) complex subunit e, mitochondrial

ATP synthase F(0) complex subunit e, mitochondrial (ATP5ME) is a protein from Homo sapiens identified by UniProt accession P56385, 69 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit e, mitochondrial
UniProt accession	P56385
Gene	ATP5ME
Organism	Homo sapiens
Length	69 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

retinitis pigmentosa · score 0.33
neoplasm · score 0.02
chronic kidney disease · score 0.02
sarcoma · score 0.01
systemic juvenile idiopathic arthritis · score 0.01
nonpapillary renal cell carcinoma · score 0.01
cancer · score 0.00
atherosclerosis · score 0.00
preeclampsia · score 0.00
non-alcoholic fatty liver disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P56385-F1	alphafold	PREDICTED	91.71	—

Amino-acid sequence (69 residues)

MVPPVQVSPL IKLGRYSALF LGVAYGATRY NYLKPRAEEE RRIAAEEKKK QDELKRIARE LAEDDSILK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit e, mitochondrial (ATP5ME)