Galectin-4 (LGALS4)

Homo sapiens — UniProt P56470

Gene: LGALS4Homo sapiensSwissProt reviewed

About Galectin-4

Galectin-4 (LGALS4) is a protein from Homo sapiens identified by UniProt accession P56470, 323 residues long. MolForge cross-references it against 0 known binders and 202 disease associations.

Target properties

Protein nameGalectin-4
UniProt accessionP56470
GeneLGALS4
OrganismHomo sapiens
Length323 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (202)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.30
  • blood protein measurement · score 0.15
  • neoplasm · score 0.10
  • Barrett's esophagus · score 0.09
  • diabetes mellitus · score 0.09
  • hepatocellular carcinoma · score 0.08
  • ulcerative colitis · score 0.08
  • Stroke · score 0.08
  • cancer · score 0.07
  • cyst · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P56470-F1alphafoldPREDICTED89.64—

Amino-acid sequence (323 residues)

MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI

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Quick facts

UniProtP56470
GeneLGALS4
OrganismHomo sapiens
Length323
Binders0
Diseases202
View on UniProt