About Galectin-4
Galectin-4 (LGALS4) is a protein
from Homo sapiens identified by UniProt accession
P56470, 323 residues long.
MolForge cross-references it against 0 known binders and
202 disease associations.
Target properties
| Protein name | Galectin-4 |
| UniProt accession | P56470 |
| Gene | LGALS4 |
| Organism | Homo sapiens |
| Length | 323 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (202)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- blood protein measurement · score 0.15
- neoplasm · score 0.10
- Barrett's esophagus · score 0.09
- diabetes mellitus · score 0.09
- hepatocellular carcinoma · score 0.08
- ulcerative colitis · score 0.08
- Stroke · score 0.08
- cancer · score 0.07
- cyst · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P56470-F1 | alphafold | PREDICTED | 89.64 | — |
Amino-acid sequence (323 residues)
MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI
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