About Caveolin-3
Caveolin-3 (CAV3) is a protein
from Homo sapiens identified by UniProt accession
P56539, 151 residues long.
MolForge cross-references it against 0 known binders and
384 disease associations.
Target properties
| Protein name | Caveolin-3 |
|---|
| UniProt accession | P56539 |
|---|
| Gene | CAV3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 151 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (384)
Diseases linked to this target (Open Targets).
- rippling muscle disease 2 · score 0.80
- long QT syndrome 9 · score 0.73
- Romano-Ward syndrome · score 0.67
- isolated asymptomatic elevation of creatine phosphokinase · score 0.62
- distal myopathy · score 0.61
- hypertrophic cardiomyopathy 1 · score 0.59
- sudden infant death syndrome · score 0.57
- limb-girdle muscular dystrophy · score 0.56
- rippling muscle disease · score 0.56
- Prolonged QT interval · score 0.55
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56539-F1 | alphafold | PREDICTED | 88.48 | — |
Amino-acid sequence (151 residues)
MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG TYSFDGVWKV SYTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI WAVVPCIKSY LIEIQCISHI YSLCIRTFCN PLFAALGQVC SSIKVVLRKE V
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