ADP-ribosylation factor-like protein 4C (ARL4C)

Homo sapiens — UniProt P56559

Gene: ARL4CHomo sapiensSwissProt reviewed

About ADP-ribosylation factor-like protein 4C

ADP-ribosylation factor-like protein 4C (ARL4C) is a protein from Homo sapiens identified by UniProt accession P56559, 192 residues long. MolForge cross-references it against 0 known binders and 113 disease associations.

Target properties

Protein nameADP-ribosylation factor-like protein 4C
UniProt accessionP56559
GeneARL4C
OrganismHomo sapiens
Length192 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (113)

Diseases linked to this target (Open Targets).

  • bilirubin measurement · score 0.35
  • cortical surface area measurement · score 0.29
  • brain measurement · score 0.29
  • diastolic blood pressure · score 0.27
  • response to high sodium diet · score 0.27
  • response to dietary potassium supplementation · score 0.27
  • central corneal thickness · score 0.26
  • hip bone size · score 0.25
  • coronary artery disease · score 0.23
  • cortical thickness · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P56559-F1alphafoldPREDICTED93.37—

Amino-acid sequence (192 residues)

MGNISSNISA FQSLHIVMLG LDSAGKTTVL YRLKFNEFVN TVPTIGFNTE KIKLSNGTAK GISCHFWDVG GQEKLRPLWK SYSRCTDGII YVVDSVDVDR LEEAKTELHK VTKFAENQGT PLLVIANKQD LPKSLPVAEI EKQLALHELI PATTYHVQPA CAIIGEGLTE GMDKLYEMIL KRRKSLKQKK KR

Explore ADP-ribosylation factor-like protein 4C with MolForge

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Quick facts

UniProtP56559
GeneARL4C
OrganismHomo sapiens
Length192
Binders0
Diseases113
View on UniProt