About Nucleoside diphosphate kinase 5
Nucleoside diphosphate kinase 5 (NME5) is a protein
from Homo sapiens identified by UniProt accession
P56597, 212 residues long.
MolForge cross-references it against 0 known binders and
102 disease associations.
Target properties
| Protein name | Nucleoside diphosphate kinase 5 |
|---|
| UniProt accession | P56597 |
|---|
| Gene | NME5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (102)
Diseases linked to this target (Open Targets).
- ciliary dyskinesia, primary, 48, without situs inversus · score 0.54
- primary ciliary dyskinesia · score 0.38
- neuroinflammatory disorder · score 0.22
- body height · score 0.20
- body composition measurement · score 0.13
- seasonal allergic rhinitis · score 0.12
- lean body mass · score 0.10
- Eczematoid dermatitis · score 0.09
- allergic rhinitis · score 0.08
- azoospermia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56597-F1 | alphafold | PREDICTED | 90.04 | — |
Amino-acid sequence (212 residues)
MEISMPPPQI YVEKTLAIIK PDIVDKEEEI QDIILRSGFT IVQRRKLRLS PEQCSNFYVE KYGKMFFPNL TAYMSSGPLV AMILARHKAI SYWLELLGPN NSLVAKETHP DSLRAIYGTD DLRNALHGSN DFAAAEREIR FMFPEVIVEP IPIGQAAKDY LNLHIMPTLL EGLTELCKQK PADPLIWLAD WLLKNNPNKP KLCHHPIVEE PY
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