About Protein Wnt-3a
Protein Wnt-3a (WNT3A) is a protein
from Homo sapiens identified by UniProt accession
P56704, 352 residues long.
MolForge cross-references it against 0 known binders and
351 disease associations.
Target properties
| Protein name | Protein Wnt-3a |
|---|
| UniProt accession | P56704 |
|---|
| Gene | WNT3A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 352 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (351)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- body height · score 0.30
- cortical thickness · score 0.28
- hypertension · score 0.26
- cardiovascular disease · score 0.26
- endometrial cancer · score 0.25
- diastolic blood pressure · score 0.24
- blood pressure · score 0.24
- mean arterial pressure · score 0.24
- systolic blood pressure · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56704-F1 | alphafold | PREDICTED | 88.32 | — |
Amino-acid sequence (352 residues)
MAPLGYFLLL CSLKQALGSY PIWWSLAVGP QYSSLGSQPI LCASIPGLVP KQLRFCRNYV EIMPSVAEGI KIGIQECQHQ FRGRRWNCTT VHDSLAIFGP VLDKATRESA FVHAIASAGV AFAVTRSCAE GTAAICGCSS RHQGSPGKGW KWGGCSEDIE FGGMVSREFA DARENRPDAR SAMNRHNNEA GRQAIASHMH LKCKCHGLSG SCEVKTCWWS QPDFRAIGDF LKDKYDSASE MVVEKHRESR GWVETLRPRY TYFKVPTERD LVYYEASPNF CEPNPETGSF GTRDRTCNVS SHGIDGCDLL CCGRGHNARA ERRREKCRCV FHWCCYVSCQ ECTRVYDVHT CK
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