About Protein Wnt-7b
Protein Wnt-7b (WNT7B) is a protein
from Homo sapiens identified by UniProt accession
P56706, 349 residues long.
MolForge cross-references it against 0 known binders and
205 disease associations.
Target properties
| Protein name | Protein Wnt-7b |
|---|
| UniProt accession | P56706 |
|---|
| Gene | WNT7B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 349 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (205)
Diseases linked to this target (Open Targets).
- Matthew-Wood syndrome · score 0.55
- refractive error measurement · score 0.51
- hemoglobin measurement · score 0.50
- hematocrit · score 0.49
- erythrocyte count · score 0.49
- frozen shoulder · score 0.47
- microphthalmia · score 0.46
- Palmar Fibromatosis · score 0.45
- Fasciitis · score 0.45
- body height · score 0.44
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56706-F1 | alphafold | PREDICTED | 90.62 | — |
Amino-acid sequence (349 residues)
MHRNFRKWIF YVFLCFGVLY VKLGALSSVV ALGANIICNK IPGLAPRQRA ICQSRPDAII VIGEGAQMGI NECQYQFRFG RWNCSALGEK TVFGQELRVG SREAAFTYAI TAAGVAHAVT AACSQGNLSN CGCDREKQGY YNQAEGWKWG GCSADVRYGI DFSRRFVDAR EIKKNARRLM NLHNNEAGRK VLEDRMQLEC KCHGVSGSCT TKTCWTTLPK FREVGHLLKE KYNAAVQVEV VRASRLRQPT FLRIKQLRSY QKPMETDLVY IEKSPNYCEE DAATGSVGTQ GRLCNRTSPG ADGCDTMCCG RGYNTHQYTK VWQCNCKFHW CCFVKCNTCS ERTEVFTCK
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