About Claudin-15
Claudin-15 (CLDN15) is a protein
from Homo sapiens identified by UniProt accession
P56746, 228 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Claudin-15 |
|---|
| UniProt accession | P56746 |
|---|
| Gene | CLDN15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- endometrial cancer · score 0.23
- glioblastoma multiforme · score 0.16
- head and neck squamous cell carcinoma · score 0.15
- mean corpuscular hemoglobin · score 0.11
- gastric adenocarcinoma · score 0.09
- malignant pleural mesothelioma · score 0.08
- appendicular lean mass · score 0.08
- hemoglobin measurement · score 0.07
- microvillus inclusion disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56746-F1 | alphafold | PREDICTED | 81.82 | — |
Amino-acid sequence (228 residues)
MSMAVETFGF FMATVGLLML GVTLPNSYWR VSTVHGNVIT TNTIFENLWF SCATDSLGVY NCWEFPSMLA LSGYIQACRA LMITAILLGF LGLLLGIAGL RCTNIGGLEL SRKAKLAATA GALHILAGIC GMVAISWYAF NITRDFFDPL YPGTKYELGP ALYLGWSASL ISILGGLCLC SACCCGSDED PAASARRPYQ APVSVMPVAT SDQEGDSSFG KYGRNAYV
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