About Claudin-17
Claudin-17 (CLDN17) is a protein
from Homo sapiens identified by UniProt accession
P56750, 224 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Claudin-17 |
|---|
| UniProt accession | P56750 |
|---|
| Gene | CLDN17 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.28
- breast adenocarcinoma · score 0.25
- endometrial cancer · score 0.23
- smoking status measurement · score 0.18
- substance abuse · score 0.17
- antisocial behaviour measurement · score 0.17
- attention deficit hyperactivity disorder · score 0.17
- glioblastoma multiforme · score 0.16
- gastric adenocarcinoma · score 0.09
- nasopharyngeal neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56750-F1 | alphafold | PREDICTED | 78.49 | — |
Amino-acid sequence (224 residues)
MAFYPLQIAG LVLGFLGMVG TLATTLLPQW RVSAFVGSNI IVFERLWEGL WMNCIRQARV RLQCKFYSSL LALPPALETA RALMCVAVAL SLIALLIGIC GMKQVQCTGS NERAKAYLLG TSGVLFILTG IFVLIPVSWT ANIIIRDFYN PAIHIGQKRE LGAALFLGWA SAAVLFIGGG LLCGFCCCNR KKQGYRYPVP GYRVPHTDKR RNTTMLSKTS TSYV
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