Epididymal secretory protein E3-beta (EDDM3B)

About Epididymal secretory protein E3-beta

Epididymal secretory protein E3-beta (EDDM3B) is a protein from Homo sapiens identified by UniProt accession P56851, 147 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Epididymal secretory protein E3-beta
UniProt accession	P56851
Gene	EDDM3B
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.31
linear and whorled nevoid hypermelanosis · score 0.05
chronic myeloproliferative disorder · score 0.04
Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
iridocorneal endothelial syndrome · score 0.04
eosinophil peroxidase deficiency · score 0.04
neutropenia, severe congenital, 1, autosomal dominant · score 0.04
idiopathic hypereosinophilic syndrome · score 0.03
ichthyosis prematurity syndrome · score 0.03
chronic myelogenous leukemia · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P56851-F1	alphafold	PREDICTED	90.11	—

Amino-acid sequence (147 residues)

MASSLKIWGT LLALLCILCT LLVQSKEVSW REFMKQHYLS PSREFREYKC DVLMRENEAL KDKSSHMFIY ISWYKIEHIC TSDNWMDRFR NAYVWVQNPL KVLKCHQENS KNSYTESRSF NYIEFHCSMD GYVDSIEDLK MVEPIGN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards