About Claudin-20
Claudin-20 (CLDN20) is a protein
from Homo sapiens identified by UniProt accession
P56880, 219 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Claudin-20 |
|---|
| UniProt accession | P56880 |
|---|
| Gene | CLDN20 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 219 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.32
- body height · score 0.31
- vital capacity · score 0.30
- appendicular lean mass · score 0.28
- endometrial cancer · score 0.23
- fat body mass · score 0.23
- forced expiratory volume · score 0.18
- whole body water mass · score 0.15
- base metabolic rate measurement · score 0.15
- body weight · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56880-F1 | alphafold | PREDICTED | 82.21 | — |
Amino-acid sequence (219 residues)
MASAGLQLLA FILALSGVSG VLTATLLPNW KVNVDVDSNI ITAIVQLHGL WMDCTWYSTG MFSCALKHSI LSLPIHVQAA RATMVLACVL SALGICTSTV GMKCTRLGGD RETKSHASFA GGVCFMSAGI SSLISTVWYT KEIIANFLDL TVPESNKHEP GGAIYIGFIS AMLLFISGMI FCTSCIKRNP EARLDPPTQQ PISNTQLENN STHNLKDYV
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