About Homeobox protein goosecoid
Homeobox protein goosecoid (GSC) is a protein
from Homo sapiens identified by UniProt accession
P56915, 257 residues long.
MolForge cross-references it against 0 known binders and
245 disease associations.
Target properties
| Protein name | Homeobox protein goosecoid |
|---|
| UniProt accession | P56915 |
|---|
| Gene | GSC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 257 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (245)
Diseases linked to this target (Open Targets).
- short stature-auditory canal atresia-mandibular hypoplasia-skeletal anomalies syndrome · score 0.73
- neurodegenerative disease · score 0.52
- Cleft palate · score 0.26
- cleft lip · score 0.26
- nose morphology measurement · score 0.25
- balding measurement · score 0.24
- hip geometry · score 0.24
- alopecia · score 0.24
- hair shape measurement · score 0.23
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P56915-F1 | alphafold | PREDICTED | 63.84 | — |
Amino-acid sequence (257 residues)
MPASMFSIDN ILAARPRCKD SVLPVAHSAA APVVFPALHG DSLYGASGGA SSDYGAFYPR PVAPGGAGLP AAVSGSRLGY NNYFYGQLHV QAAPVGPACC GAVPPLGAQQ CSCVPTPPGY EGPGSVLVSP VPHQMLPYMN VGTLSRTELQ LLNQLHCRRK RRHRTIFTDE QLEALENLFQ ETKYPDVGTR EQLARKVHLR EEKVEVWFKN RRAKWRRQKR SSSEESENAE KWNKTSSSKA SPEKREEEGK SDLDSDS
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