Protein ripply3 (RIPPLY3)

About Protein ripply3

Protein ripply3 (RIPPLY3) is a protein from Homo sapiens identified by UniProt accession P57055, 190 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Protein ripply3
UniProt accession	P57055
Gene	RIPPLY3
Organism	Homo sapiens
Length	190 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
birth weight · score 0.29
intelligence · score 0.15
hemoglobin measurement · score 0.07
red blood cell density measurement · score 0.05
hematocrit · score 0.05
mean arterial pressure · score 0.04
erythrocyte count · score 0.04
Truncus arteriosus · score 0.04
pancreatic adenocarcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P57055-F1	alphafold	PREDICTED	60.40	—

Amino-acid sequence (190 residues)

MEPEAAAGAR KARGRGCHCP GDAPWRPPPP RGPESPAPWR PWIQTPGDAE LTRTGRPLEP RADQHTFGSK GAFGFQHPVR VYLPMSKRQE YLRSSGEQVL ASFPVQATID FYDDESTESA SEAEEPEEGP PPLHLLPQEV GGRQENGPGG KGRDQGINQG QRSSGGGDHW GEGPLPQGVS SRGGKCSSSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards