MAP3K7 C-terminal-like protein (MAP3K7CL)

About MAP3K7 C-terminal-like protein

MAP3K7 C-terminal-like protein (MAP3K7CL) is a protein from Homo sapiens identified by UniProt accession P57077, 142 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein name	MAP3K7 C-terminal-like protein
UniProt accession	P57077
Gene	MAP3K7CL
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (51)

Diseases linked to this target (Open Targets).

electrocardiography · score 0.39
neutrophil count · score 0.35
leukocyte count · score 0.32
coronary artery disease · score 0.32
serum gamma-glutamyl transferase measurement · score 0.28
myeloid white cell count · score 0.27
body height · score 0.27
sitting height measurement · score 0.24
serum alanine aminotransferase measurement · score 0.22
bilirubin measurement · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P57077-F1	alphafold	PREDICTED	84.17	—

Amino-acid sequence (142 residues)

MISTARVPAD KPVRIAFSLN DASDDTPPED SIPLVFPELD QQLQPLPPCH DSEESMEVFK QHCQIAEEYH EVKKEITLLE QRKKELIAKL DQAEKEKVDA AELVREFEAL TEENRTLRLA QSQCVEQLEK LRIQYQKRQG SS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards