SCAN domain-containing protein 1 (SCAND1)

About SCAN domain-containing protein 1

SCAN domain-containing protein 1 (SCAND1) is a protein from Homo sapiens identified by UniProt accession P57086, 179 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	SCAN domain-containing protein 1
UniProt accession	P57086
Gene	SCAND1
Organism	Homo sapiens
Length	179 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

lean body mass · score 0.14
fat body mass · score 0.13
whole body water mass · score 0.12
cancer · score 0.09
neoplasm · score 0.08
body height · score 0.08
base metabolic rate measurement · score 0.07
appendicular lean mass · score 0.07
body weight · score 0.06
basal cell carcinoma · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P57086-F1	alphafold	PREDICTED	69.98	—

Amino-acid sequence (179 residues)

MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM LVQEQLLAIL PEAARARRIR RRTDVRITG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards