Regulator of G-protein signaling 8 (RGS8)

About Regulator of G-protein signaling 8

Regulator of G-protein signaling 8 (RGS8) is a protein from Homo sapiens identified by UniProt accession P57771, 180 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Regulator of G-protein signaling 8
UniProt accession	P57771
Gene	RGS8
Organism	Homo sapiens
Length	180 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P57771-F1	alphafold	PREDICTED	81.26	—

Amino-acid sequence (180 residues)

MAALLMPRRN KGMRTRLGCL SHKSDSCSDF TAILPDKPNR ALKRLSTEEA TRWADSFDVL LSHKYGVAAF RAFLKTEFSE ENLEFWLACE EFKKTRSTAK LVSKAHRIFE EFVDVQAPRE VNIDFQTREA TRKNLQEPSL TCFDQAQGKV HSLMEKDSYP RFLRSKMYLD LLSQSQRRLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards