About Calcium-binding protein 4
Calcium-binding protein 4 (CABP4) is a protein
from Homo sapiens identified by UniProt accession
P57796, 275 residues long.
MolForge cross-references it against 0 known binders and
77 disease associations.
Target properties
| Protein name | Calcium-binding protein 4 |
|---|
| UniProt accession | P57796 |
|---|
| Gene | CABP4 |
|---|
| Organism | Homo sapiens |
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| Length | 275 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (77)
Diseases linked to this target (Open Targets).
- congenital stationary night blindness · score 0.71
- Retinal dystrophy · score 0.45
- Cone rod dystrophy · score 0.43
- cone-rod dystrophy · score 0.43
- autosomal dominant nocturnal frontal lobe epilepsy · score 0.38
- achromatopsia · score 0.36
- Usher syndrome · score 0.27
- Åland Islands eye disease · score 0.26
- cone dystrophy · score 0.26
- genetic disorder · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P57796-F1 | alphafold | PREDICTED | 64.37 | — |
Amino-acid sequence (275 residues)
MTTEQARGQQ GPNLAIGRQK PPAGVVTPKS DAEEPPLTRK RSKKERGLRG SRKRTGSSGE QTGPEAPGSS NNPPSTGEGP AGAPPASPGP ASSRQSHRHR PDSLHDAAQR TYGPLLNRVF GKDRELGPEE LDELQAAFEE FDTDRDGYIS HRELGDCMRT LGYMPTEMEL LEVSQHIKMR MGGRVDFEEF VELIGPKLRE ETAHMLGVRE LRIAFREFDR DRDGRITVAE LREAVPALLG EPLAGPELDE MLREVDLNGD GTVDFDEFVM MLSRH
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