Inhibin beta E chain (INHBE)

About Inhibin beta E chain

Inhibin beta E chain (INHBE) is a protein from Homo sapiens identified by UniProt accession P58166, 350 residues long. MolForge cross-references it against 0 known binders and 377 disease associations.

Target properties

Protein name	Inhibin beta E chain
UniProt accession	P58166
Gene	INHBE
Organism	Homo sapiens
Length	350 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (377)

Diseases linked to this target (Open Targets).

platelet count · score 0.29
high density lipoprotein cholesterol measurement · score 0.27
lymphocyte count · score 0.22
endometrial cancer · score 0.18
cutaneous melanoma · score 0.18
lung adenocarcinoma · score 0.18
birth weight · score 0.16
platelet crit · score 0.14
BMI-adjusted waist-hip ratio · score 0.14
neoplasm · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P58166-F1	alphafold	PREDICTED	74.36	—

Amino-acid sequence (350 residues)

MRLPDVQLWL VLLWALVRAQ GTGSVCPSCG GSKLAPQAER ALVLELAKQQ ILDGLHLTSR PRITHPPPQA ALTRALRRLQ PGSVAPGNGE EVISFATVTD STSAYSSLLT FHLSTPRSHH LYHARLWLHV LPTLPGTLCL RIFRWGPRRR RQGSRTLLAE HHITNLGWHT LTLPSSGLRG EKSGVLKLQL DCRPLEGNST VTGQPRRLLD TAGHQQPFLE LKIRANEPGA GRARRRTPTC EPATPLCCRR DHYVDFQELG WRDWILQPEG YQLNYCSGQC PPHLAGSPGI AASFHSAVFS LLKANNPWPA STSCCVPTAR RPLSLLYLDH NGNVVKTDVP DMVVEACGCS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards