About Olfactory receptor 2B6
Olfactory receptor 2B6 (OR2B6) is a protein
from Homo sapiens identified by UniProt accession
P58173, 313 residues long.
MolForge cross-references it against 0 known binders and
46 disease associations.
Target properties
| Protein name | Olfactory receptor 2B6 |
|---|
| UniProt accession | P58173 |
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| Gene | OR2B6 |
|---|
| Organism | Homo sapiens |
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| Length | 313 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (46)
Diseases linked to this target (Open Targets).
- pancreatic adenocarcinoma · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- seasonal allergic rhinitis · score 0.13
- platelet-to-lymphocyte ratio · score 0.11
- FEV/FVC ratio · score 0.10
- breast carcinoma · score 0.08
- psoriasis · score 0.06
- multiple sclerosis · score 0.04
- central nervous system cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P58173-F1 | alphafold | PREDICTED | 88.05 | — |
Amino-acid sequence (313 residues)
MNWVNDSIIQ EFILLGFSDR PWLEFPLLVV FLISYTVTIF GNLTIILVSR LDTKLHTPMY FFLTNLSLLD LCYTTCTVPQ MLVNLCSIRK VISYRGCVAQ LFIFLALGAT EYLLLAVMSF DRFVAICRPL HYSVIMHQRL CLQLAAASWV TGFSNSVWLS TLTLQLPLCD PYVIDHFLCE VPALLKLSCV ETTANEAELF LVSELFHLIP LTLILISYAF IVRAVLRIQS AEGRQKAFGT CGSHLIVVSL FYSTAVSVYL QPPSPSSKDQ GKMVSLFYGI IAPMLNPLIY TLRNKEVKEG FKRLVARVFL IKK
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