About Olfactory receptor 4D2
Olfactory receptor 4D2 (OR4D2) is a protein
from Homo sapiens identified by UniProt accession
P58180, 307 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 4D2 |
|---|
| UniProt accession | P58180 |
|---|
| Gene | OR4D2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 307 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- clear cell renal carcinoma · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- retinoschisis · score 0.09
- blood protein measurement · score 0.03
- eosinophil count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P58180-F1 | alphafold | PREDICTED | 89.81 | — |
Amino-acid sequence (307 residues)
METGNLTWVS DFVFLGLSQT RELQRFLFLM FLFVYITTVM GNILIIITVT SDSQLHTPMY FLLRNLAVLD LCFSSVTAPK MLVDLLSEKK TISYQGCMGQ IFFFHFLGGA MVFFLSVMAF DRLIAISRPL RYVTVMNTQL WVGLVVATWV GGFVHSIVQL ALMLPLPFCG PNILDNFYCD VPQVLRLACT DTSLLEFLKI SNSGLLDVVW FFLLLMSYLF ILVMLRSHPG EARRKAASTC TTHIIVVSMI FVPSIYLYAR PFTPFPMDKL VSIGHTVMTP MLNPMIYTLR NQDMQAAVRR LGRHRLV
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