About Olfactory receptor 10A3
Olfactory receptor 10A3 (OR10A3) is a protein
from Homo sapiens identified by UniProt accession
P58181, 314 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Olfactory receptor 10A3 |
|---|
| UniProt accession | P58181 |
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| Gene | OR10A3 |
|---|
| Organism | Homo sapiens |
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| Length | 314 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- atopic eczema · score 0.18
- diet measurement · score 0.07
- lean body mass · score 0.03
- appendicular lean mass · score 0.02
- whole body water mass · score 0.02
- fat body mass · score 0.02
- smoking status measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P58181-F1 | alphafold | PREDICTED | 88.28 | — |
Amino-acid sequence (314 residues)
MKRQNQSCVV EFILLGFSNF PELQVQLFGV FLVIYVVTLM GNAIITVIIS LNQSLHVPMY LFLLNLSVVE VSFSAVITPE MLVVLSTEKT MISFVGCFAQ MYFILLFGGT ECFLLGAMAY DRFAAICHPL NYPVIMNRGV FMKLVIFSWI SGIMVATVQT TWVFSFPFCG PNEINHLFCE TPPVLELVCA DTFLFEIYAF TGTILIVMVP FLLILLSYIR VLFAILKMPS TTGRQKAFST CASHLTSVTL FYGTANMTYL QPKSGYSPET KKLISLAYTL LTPLLNPLIY SLRNSEMKRT LIKLWRRKVI LHTF
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