About Olfactory receptor 12D2
Olfactory receptor 12D2 (OR12D2) is a protein
from Homo sapiens identified by UniProt accession
P58182, 307 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Olfactory receptor 12D2 |
|---|
| UniProt accession | P58182 |
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| Gene | OR12D2 |
|---|
| Organism | Homo sapiens |
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| Length | 307 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- hepatocellular carcinoma · score 0.18
- low grade glioma · score 0.18
- mean corpuscular hemoglobin · score 0.12
- BMI-adjusted hip circumference · score 0.06
- insomnia measurement · score 0.04
- urate measurement · score 0.04
- schizophrenia · score 0.03
- MHC class I polypeptide-related sequence A measurement · score 0.03
- Autism · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P58182-F1 | alphafold | PREDICTED | 85.47 | — |
Amino-acid sequence (307 residues)
MLNTTSVTEF LLLGVTDIQE LQPFLFVVFL TIYFISVTGN GAVLMIVISD PRLHSLMYFF LGNLSYLDIC YSTVTLPKML QNFLSTHKAI SFLGCISQLH FFHSLGSTES MLFAVMAFDL SVAICKPLRY TVIMNPQLCT QMAITIWVIG FFHALLHSVM TSRLNFCGSN RIHHFLCDIK PLLKLACGNT ELNQWLLSTV TGTIAMGPFF LTLLSYFYII TYLFFKTRSC SMLCKALSTC ASHFMVVILF YAPVLFTYIH PALESFMDQD RIVAIMYTVV TPVLNPLIYT LRNKEVKGAL GRVIRRL
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