About Protein FAM3B
Protein FAM3B (FAM3B) is a protein
from Homo sapiens identified by UniProt accession
P58499, 235 residues long.
MolForge cross-references it against 0 known binders and
136 disease associations.
Target properties
| Protein name | Protein FAM3B |
|---|
| UniProt accession | P58499 |
|---|
| Gene | FAM3B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 235 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (136)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.44
- cancer biomarker measurement · score 0.31
- serum carcinoembryonic antigen measurement · score 0.30
- self reported educational attainment · score 0.19
- body mass index · score 0.18
- schizophrenia · score 0.14
- intelligence · score 0.14
- cognitive function measurement · score 0.11
- mathematical ability · score 0.11
- gastroesophageal reflux disease · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P58499-F1 | alphafold | PREDICTED | 93.14 | — |
Amino-acid sequence (235 residues)
MRPLAGGLLK VVFVVFASLC AWYSGYLLAE LIPDAPLSSA AYSIRSIGER PVLKAPVPKR QKCDHWTPCP SDTYAYRLLS GGGRSKYAKI CFEDNLLMGE QLGNVARGIN IAIVNYVTGN VTATRCFDMY EGDNSGPMTK FIQSAAPKSL LFMVTYDDGS TRLNNDAKNA IEALGSKEIR NMKFRSSWVF IAAKGLELPS EIQREKINHS DAKNNRYSGW PAEIQIEGCI PKERS
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