FXYD domain-containing ion transport regulator 7…

About FXYD domain-containing ion transport regulator 7

FXYD domain-containing ion transport regulator 7 (FXYD7) is a protein from Homo sapiens identified by UniProt accession P58549, 80 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	FXYD domain-containing ion transport regulator 7
UniProt accession	P58549
Gene	FXYD7
Organism	Homo sapiens
Length	80 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

endometrial cancer · score 0.11
mean platelet volume · score 0.09
reticulocyte count · score 0.09
platelet count · score 0.08
Immature Reticulocyte Fraction Measurement · score 0.07
platelet component distribution width · score 0.06
age-related hearing impairment · score 0.06
monocyte count · score 0.06
Red cell distribution width · score 0.05
hemoglobin measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P58549-F1	alphafold	PREDICTED	70.56	—

Amino-acid sequence (80 residues)

MATPTQTPTK APEEPDPFYY DYNTVQTVGM TLATILFLLG ILIVISKKVK CRKADSRSES PTCKSCKSEL PSSAPGGGGV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

FXYD domain-containing ion transport regulator 7 (FXYD7)