Endoribonuclease YbeY (YBEY)

About Endoribonuclease YbeY

Endoribonuclease YbeY (YBEY) is a protein from Homo sapiens identified by UniProt accession P58557, 167 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	Endoribonuclease YbeY
UniProt accession	P58557
Gene	YBEY
Organism	Homo sapiens
Length	167 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.35
Testicular Germ Cell Tumor · score 0.15
testicular carcinoma · score 0.15
lymphocyte count · score 0.13
platelet count · score 0.12
monocyte percentage of leukocytes · score 0.12
leukocyte count · score 0.11
neutrophil count · score 0.11
reticulocyte count · score 0.09
heel bone mineral density · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P58557-F1	alphafold	PREDICTED	96.22	—

Amino-acid sequence (167 residues)

MSLVIRNLQR VIPIRRAPLR SKIEIVRRIL GVQKFDLGII CVDNKNIQHI NRIYRDRNVP TDVLSFPFHE HLKAGEFPQP DFPDDYNLGD IFLGVEYIFH QCKENEDYND VLTVTATHGL CHLLGFTHGT EAEWQQMFQK EKAVLDELGR RTGTRLQPLT RGLFGGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards