About Protein eva-1 homolog C
Protein eva-1 homolog C (EVA1C) is a protein
from Homo sapiens identified by UniProt accession
P58658, 441 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Protein eva-1 homolog C |
|---|
| UniProt accession | P58658 |
|---|
| Gene | EVA1C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 441 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.36
- body height · score 0.27
- serum gamma-glutamyl transferase measurement · score 0.27
- serum alanine aminotransferase measurement · score 0.26
- motor neuron disease · score 0.05
- testosterone measurement · score 0.03
- clear cell renal carcinoma · score 0.02
- glioblastoma multiforme · score 0.01
- large cell medulloblastoma · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P58658-F1 | alphafold | PREDICTED | 70.24 | — |
Amino-acid sequence (441 residues)
MLLPGRARQP PTPQPVQHPG LRRQVEPPGQ LLRLFYCTVL VCSKEISALT DFSGYLTKLL QNHTTYACDG DYLNLQCPRH STISVQSAFY GQDYQMCSSQ KPASQREDSL TCVAATTFQK VLDECQNQRA CHLLVNSRVF GPDLCPGSSK YLLVSFKCQP NELKNKTVCE DQELKLHCHE SKFLNIYSAT YGRRTQERDI CSSKAERLPP FDCLSYSALQ VLSRRCYGKQ RCKIIVNNHH FGSPCLPGVK KYLTVTYACV PKNILTAIDP AIANLKPSLK QKDGEYGINF DPSGSKVLRK DGILVSNSLA AFAYIRAHPE RAALLFVSSV CIGLALTLCA LVIRESCAKD FRDLQLGREQ LVPGSDKVEE DSEDEEEEED PSESDFPGEL SGFCRTSYPI YSSIEAAELA ERIERREQII QEIWMNSGLD TSLPRNMGQF Y
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