Rhomboid-related protein 3 (RHBDL3)

About Rhomboid-related protein 3

Rhomboid-related protein 3 (RHBDL3) is a protein from Homo sapiens identified by UniProt accession P58872, 404 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	Rhomboid-related protein 3
UniProt accession	P58872
Gene	RHBDL3
Organism	Homo sapiens
Length	404 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P58872-F1	alphafold	PREDICTED	79.67	—

Amino-acid sequence (404 residues)

MGEHPSPGPA VAACAEAERI EELEPEAEER LPAAPEDHWK VLFDQFDPGN TGYISTGKFR SLLESHSSKL DPHKREVLLA LADSHADGQI GYQDFVSLMS NKRSNSFRQA ILQGNRRLSS KALLEEKGLS LSQRLIRHVA YETLPREIDR KWYYDSYTCC PPPWFMITVT LLEVAFFLYN GVSLGQFVLQ VTHPRYLKNS LVYHPQLRAQ VWRYLTYIFM HAGIEHLGLN VVLQLLVGVP LEMVHGATRI GLVYVAGVVA GSLAVSVADM TAPVVGSSGG VYALVSAHLA NIVMNWSGMK CQFKLLRMAV ALICMSMEFG RAVWLRFHPS AYPPCPHPSF VAHLGGVAVG ITLGVVVLRN YEQRLQDQSL WWIFVAMYTV FVLFAVFWNI FAYTLLDLKL PPPP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards